Formed in 1973, the group's surgeons practice in twelve subspecialties , a degree of subspecialization unmatched in Houston and the nation. Because of its physicians' long-standing reputations for leadership in the field of orthopedic surgery, as well as in teaching and research, Fondren Orthopedic Group L.L.P. has become one of the nation's most respected and well-established orthopedic practices.

In addition to the Texas Orthopedic Hospital location, Fondren has various locations around the city including offices in Baytown, Pearland, Kingwood, Pasadena, Sugar Land, The Woodlands and Webster.